Endocrine Abstracts

Background: We aim to test whether plasma copeptin (copeptin), the C-terminal fragment of vasopressin, has predictive value of cardiovascular events in patients with type 2 diabetes without previous cardiovascular disease who were treated in primary care.Methods: We measured copeptin in 697 patients who participated in the epidemiological study CARDIPP (Cardiovascular Risk Factors in Patients with Diabetes – a Prospective Study in Primary Care; Clin...

Background: Individuals with diabetes are at higher risk for developing arterial disorders. The toe-brachial index (TBI) is associated with peripheral vascular disease, and aortic pulse-wave velocity (aPWV) is currently the gold standard for assessing arterial stiffness. High concentrations of plasma arginine vasopressin (AVP) preferentially stimulate V1a receptors, which affect the vascular bed and may contribute to cardiovascular (CV) complications. Copeptin, a more stable p...

BackgroundAccurate identification of patients at risk in the Emergency Department (ED) is crucial in order to avoid delays in treatment which may result in poor outcomes. Our aim was to study the association of the decision in ED to admit patients with chest pain and/or breathlessness in the ED to a ward with risk stratification by RETTS or NEWS and level of the surrogate biomarkers Copeptin, MR-proADM and MR-proANP of vasoregulatory hormones.<p clas...